The candidate will be joining GSK Vaccine Technical R&D Drug Substance team to work with a novel, next generation approach to the development of vaccines and immunotherapies targeting infectious and other immune mediated diseases. This novel and highly efficient vaccine technology – called Multiple Antigen Presenting System (MAPS) – enables the high affinity binding of protective polysaccharides as well as proteins in a single vaccine, uniquely inducing a broad and protective B-cell and T-cell immune response.
The MAPS Technology team, part of TRD/DS, is seeking a Co-op who is interested in the process development of different vaccine programs. The primary responsibility of the student will be to develop or optimize the process for polysaccharide purification, biotinylation and MAPS complexation. The student will also have the opportunity to analyze or characterize polysaccharides, proteins or other molecules using various analytical techniques such as HPLC, SEC-MALS, NMR, LC/MS, GC/MS, SDS-PAGE, etc., depending on his/her interests and current needs of the team.
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