Immunological Toxicology and Biomarkers is part of the Pre-Clinical Safety (PCS) department with in GSK R&D Business Unit. PCS aims to characterize, understand, and explain the biological mechanisms of the Safety of new medicines and to translate this knowledge for project teams, patients, prescribers, and regulatory agencies.
Immunological Toxicology specifically develops and executes testing strategies to investigate immunotox consequences of on-target and/or off-target engagement of compounds. We provide timely, comprehensive, and well-integrated assessments of immunotoxicity potential and risk at all phases of drug development and regulatory submissions. We support customized immunotoxicology testing on in-house and outsourced in vivo toxicology studies and continuously develop and improve in vitro and in vivo methods to assess immunotoxicity.
We are located at the Upper Providence Site in Collegeville, PA.
We are seeking a 6 month co-op student who is interested in learning and utilizing “state of the art” equipment for evaluating drug-induced effects on the immune system. The co-op student will be involved with ongoing Immunologic Toxicology projects evaluating Immune stimulation and disregulation utilizing current immunologic methods such as flow cytometry and cell based assays on samples obtained from in vitro and in vivo studies.
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