Summer Co-op/Biopharmaceutical Development

Biopharm Drug Substance Development is a highly experienced Chemistry, Manufacturing and Controls (CMC) organization accountable for delivering robust, cost-effective and competitive products and manufacturing processes spanning the full lifecycle of asset development from the pre-clinical stage through commercialization. These activities are delivered through state-of-the-art internal facilities and strategic external partners. Collectively, the team is accountable for CMC activities encompassing cell line support, cell culture/microbial fermentation, and purification development. We also pioneer innovative technologies to improve the process robustness, productivity, and to reduce the cost of goods.

The Biopharm Drug Substance Development group is searching for a Process Development Co-op to join a high-performing team of upstream scientists who are working to scale and optimize processes related to intensified perfusion cell cultures. This role will be predominantly lab-based and will require skills relating to experimental design/execution, process scaling, cell culture, performing laboratory assays, data analysis, and report writing. Specifically, you will have the opportunity to perform calculations related to the scaling of intensified N-1 perfusion bioreactor systems, culture mammalian cells to high densities using cell retention devices in small-scale bioreactors, and to analyze the cellular health and productivity. This co-op is designed to provide experience in an exciting and valuable area of biopharmaceutical manufacturing.

• Pursuing a Master's or PhD program in a Scientific discipline.
• Must have taken coursework in a relevant field such as Chemical/Biological Engineering, or a related field in Biology or Chemistry.
• Must be able to work full-time (35-40 hours/week) throughout the 6 month assignment (June~December 2024).
• Must have an active student status and/or within 12 months post-graduation from a BS or MS degree program. Post-doctoral candidates are not eligible.

• Practiced in aseptic cell culture technique and a working knowledge of routine laboratory procedures (i.e., making solutions, pipetting, notebook documentation)
• General knowledge regarding mammalian cell culture and mAb production
• Previous experience working with 3L Benchtop Bioreactors or the Ambr® 250 System
• Experience using cell retention devices, especially Alternating Tangential Flow filtration
• Proficiency with particle and cellular characterization techniques
• A general understanding of important factors in scaling biological and chemical processes

• Must successfully pass a drug screen and background check prior to assignment target start date.  
• If your skillsets are a match for this role, you will be contacted by our recruitment team with next steps to complete our internal World of GSK Assessment.
• Please note, you must receive a passing score to move forward in the interview process. Once your assessment is complete, a recruiter will review your results and be in touch with next steps.

• While GSK embraces a flexible work environment, we do require certain positions to be onsite. Candidates who are hired for an on-site or a hybrid role and reside outside of 50-miles from their assigned work location are eligible for relocation stipend. This is a one-time payment to help offset housing & relocation expenses. Please refer to the position details for the requirements of each position.
• GSK Interns and Co-ops are offered a competitive hourly pay rate and benefits. Please note, benefits eligibility to be determined upon hire.

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